TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human BACE1 proteolytic activityMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 19.9nMAssay Description:Inhibition of recombinant human BACE1 using Eu-CEVNLDAEFK-Qsy7 as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of BACE1 expressed in HEK293T cells co-transfected APP with NFEV mutation at proteolytic site by sAPP_NF cell based assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant human BACE1 expressed in CHO cells co-transfected with human APP with Swedish mutation assessed as amyloid beta1-40 secreti...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 95nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 108nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 124nMAssay Description:Inhibition of human PARP1More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 757nMAssay Description:Inhibition of recombinant human BACE1 using Eu-CEVNLDAEFK-Qsy7 as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human GLS1More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of BACE1 using Rh-EVNLDAEFK-Quencher as substrateMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of recombinant human BACE1 using Eu-CEVNLDAEFK-Qsy7 as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of recombinant human BACE1 using Eu-CEVNLDAEFK-Qsy7 as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataIC50: 3.84E+3nMAssay Description:Inhibition of recombinant human BACE1 using Eu-CEVNLDAEFK-Qsy7 as substrate by HTRF assayMore data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 4.57E+3nMAssay Description:Inhibition of human GLS1More data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of human GLS1More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.43E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.35E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.19E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.59E+4nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) aggregation incubated at 37 degC for 16 hrs by thioflavin T fluorescence assayMore data for this Ligand-Target Pair
TargetBeta-secretase 1(Homo sapiens (Human))
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Beijing Institute Of Pharmacology And Toxicology
Curated by ChEMBL
Affinity DataEC50: 43nMAssay Description:Inhibition of BACE1 expressed in HEK293T cells co-transfected APP with NFEV mutation at proteolytic site assessed as amyloid EV40 secretionMore data for this Ligand-Target Pair