Found 57 with Last Name = 'zhu' and Initial = 'mx' TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
3D Structure (crystal)TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 268nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 2.03E+3nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 2.26E+3nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 4(Mus musculus)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of rat Angiotensin I converting enzyme (ACE), using Hip-Gly-Gly as synthetic substrate.More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 4(Mus musculus)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Antagonist activity at mouse TRPC4beta expressed in HEK293 cells co-expressing MOR decrease in DAMGO-evoked intracellular calcium level by Fluo-8-AM ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 5.92E+4nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 5.97E+4nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 7.19E+4nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: 8.89E+4nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AchE using acetylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman's ...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Key Laboratory Of Combinatorial Biosynthesis And Drug Discovery (Wuhan University)
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BuChE using butyrylthiocholine iodide as substrate incubated for 20 mins prior to substrate addition measured for 1 hr by Ellman'...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mus musculus)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 2.05E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as peak current changes at +80 mV by ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mus musculus)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 1.23E+4nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 7(Homo sapiens)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 314nMAssay Description:Agonist activity at human TRPC7 expressed in HEK293 cells assessed as increase in intracellular calcium level measured for 2.5 mins in presence of 2 ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 7(Homo sapiens)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 213nMAssay Description:Agonist activity at human TRPC7 expressed in HEK293 cells assessed as increase in intracellular calcium level measured for 2.5 mins in presence of 2 ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mus musculus)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 890nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as peak current changes at +80 mV by ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mus musculus)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 8.00E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mus musculus)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 7.79E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mus musculus)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 2.88E+4nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mus musculus)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 2.00E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mus musculus)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 3.24E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as peak current changes at +80 mV by ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mus musculus)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 1.39E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mus musculus)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 1.40E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as induction of membrane potential de...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 138nMAssay Description:Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 0.5 m...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 3(Homo sapiens (Human))
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 19nMAssay Description:Agonist activity at human TRPC3 expressed in HEK293 cells assessed as induction of membrane depolarization measured for 2.5 mins in presence of 0.5 m...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mus musculus)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 4.66E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 6(Mus musculus)
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Moe) and Hubei Provinc
Curated by ChEMBL
Affinity DataEC50: 3.91E+3nMAssay Description:Agonist activity at mouse TRPC6 expressed in HEK293 cells co-expressing Gq11-PLCbeta fused M5 receptor assessed as increase in intracellular calcium ...More data for this Ligand-Target Pair
