TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Novartis Institutes For Biomedical Research And Novartis Pharma Development
Curated by ChEMBL
Novartis Institutes For Biomedical Research And Novartis Pharma Development
Curated by ChEMBL
Affinity DataIC50: 0.950nMAssay Description:Inhibitory activity against macrophilin (FKBP-12)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Novartis Institutes For Biomedical Research And Novartis Pharma Development
Curated by ChEMBL
Novartis Institutes For Biomedical Research And Novartis Pharma Development
Curated by ChEMBL
Affinity DataIC50: 1.45nMAssay Description:Inhibitory activity against macrophilin (FKBP-12)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Novartis Institutes For Biomedical Research And Novartis Pharma Development
Curated by ChEMBL
Novartis Institutes For Biomedical Research And Novartis Pharma Development
Curated by ChEMBL
Affinity DataIC50: 1.88nMAssay Description:Inhibitory activity against macrophilin (FKBP-12)More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 470nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 670nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 797nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of murine p38 alpha MAP kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.41E+3nMAssay Description:Inhibition of human p38 beta MAP kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
Affinity DataIC50: 8.09E+3nMAssay Description:Inhibition of JNK2 kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human p38 delta MAP kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of JNK1 kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:In vivo inhibition of murine Mitogen-activated protein kinase p38 alpha activity, GST-ATF-2 as substrate in the presence of 120 microM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ERK2 kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Novartis Pharma
Curated by ChEMBL
Novartis Pharma
Curated by ChEMBL
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of c-src kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+4nMAssay Description:In vivo inhibition of ram seminal vesicle Prostaglandin G/H synthase 1 activity by determining PGE-2 by RIAMore data for this Ligand-Target Pair
Affinity DataIC50: 5.11E+4nMAssay Description:Inhibition of PKCalpha kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of Prostaglandin G/H synthase 1, COX-1More data for this Ligand-Target Pair
Affinity DataIC50: 8.68E+4nMAssay Description:Inhibition of c-abl kinaseMore data for this Ligand-Target Pair