TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 6.5nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Eberhard-Karls University
Curated by ChEMBL
Eberhard-Karls University
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 113nMAssay Description:Inhibition of wild type EGFR using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation cou...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of wild type B-Raf using MEK1-KM as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 399nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of VEGFR2 using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Islamic University Of Gaza
Curated by ChEMBL
Islamic University Of Gaza
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of SRC using poly(Glu,Tyr) as substrate assessed as [33P-gamma]-ATP incorporation after 60 mins by microplate scintillation countingMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Affinity DataKd: 1.50E+4nMAssay Description:Binding affinity to human DYRK1A (127 to 485 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by isothermal...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Affinity DataKd: 7.00E+3nMAssay Description:Binding affinity to human DYRK1A (127 to 485 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by isothermal...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Affinity DataKd: 1.00E+4nMAssay Description:Binding affinity to human DYRK1A (127 to 485 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by isothermal...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Affinity DataKd: 4.00E+3nMAssay Description:Binding affinity to human DYRK1A (127 to 485 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by isothermal...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to human DYRK1A (127 to 485 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by isothermal...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Affinity DataKd: 3.80E+4nMAssay Description:Binding affinity to human DYRK1A (127 to 485 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by isothermal...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Affinity DataKd: 4.30E+4nMAssay Description:Binding affinity to human DYRK1A (127 to 485 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by isothermal...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Affinity DataKd: 1.80E+5nMAssay Description:Binding affinity to human DYRK1A (127 to 485 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by isothermal...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Eberhard Karls Universit£T T£Bingen
Curated by ChEMBL
Affinity DataKd: 4.30E+5nMAssay Description:Binding affinity to human DYRK1A (127 to 485 residues) expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by isothermal...More data for this Ligand-Target Pair