Affinity DataKi: 0.170nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.320nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.600nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.780nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.870nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.930nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 3.40nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.30nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 5.20nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.20nMAssay Description:Displacement of [3H]-naloxone from mouse MOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 8.20nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 9.20nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 34nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 46nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Competitive inhibition of human His6-tagged NEU1 expressed in HEK293 cells using 4MU-NANA as substrate preincubated with substrate for 15 mins and me...More data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Inhibitory activity against human thymidylate synthase with variable concentration of dUMP and fixed N5,10-CH2-H4PteGlu (200 uM)More data for this Ligand-Target Pair
Affinity DataKi: 62nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Mus musculus (Mouse))
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 76nMAssay Description:Displacement of [3H]-diprenorphine from mouse KOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 96nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 137nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 149nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 157nMAssay Description:Displacement of [3H]-diprenorphine from mouse DOR expressed in CHO cell membranes by competitive radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 180nMAssay Description:Competitive inhibition of human His6-tagged NEU1 expressed in HEK293 cells using 4MU-NANA as substrate preincubated with substrate for 15 mins and me...More data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Competitive inhibition of human His6-tagged NEU1 expressed in HEK293 cells using 4MU-NANA as substrate preincubated with substrate for 15 mins and me...More data for this Ligand-Target Pair
Affinity DataKi: 250nMAssay Description:Inhibitory activity against human thymidylate synthase with variable concentration of dUMP and fixed N5,10-CH2-H4PteGlu (200 uM)More data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Inhibition of human N-terminal MBP-fused NEU4 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataKi: 280nMAssay Description:Inhibition of human N-terminal MBP-fused NEU3 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataKi: 320nMAssay Description:Inhibition of human N-terminal MBP-fused NEU3 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataKi: 620nMAssay Description:Inhibition of human N-terminal MBP-fused NEU3 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataKi: 830nMAssay Description:Non-competitive inhibition of human His6-tagged NEU1 expressed in HEK293 cells using 4MU-NANA as substrate preincubated with substrate for 15 mins an...More data for this Ligand-Target Pair
Affinity DataKi: 1.30E+3nMAssay Description:Competitive inhibition of N-terminal MBP-fused human NEU2 expressed in Escherichia coli using 4MU-NANA as substrate preincubated with substrate for 1...More data for this Ligand-Target Pair
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of human N-terminal MBP-fused NEU3 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nMAssay Description:Non-competitive inhibition of N-terminal MBP-fused human NEU2 expressed in Escherichia coli using 4MU-NANA as substrate preincubated with substrate f...More data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Non-competitive inhibition of N-terminal MBP-fused human NEU2 expressed in Escherichia coli using 4MU-NANA as substrate preincubated with substrate f...More data for this Ligand-Target Pair