Compile Data Set for Download or QSAR
maximum 50k data
Found 88 with Last Name = 'zou' and Initial = 'lw'
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154561(CHEMBL3774603)
Affinity DataKi:  42nMAssay Description:Competitive inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552232(CHEMBL4776624)
Affinity DataKi:  68nMAssay Description:Mixed inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571105(CHEMBL4851375)
Affinity DataKi:  90nMAssay Description:Non-competitive inhibition of CES2 in human liver microsomes using fluorescein diacetate as substrate by Lineweaver-Burk plot based Michelis-Menten e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50017698(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human CES2A using 4-methylumbelliferone as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154561(CHEMBL3774603)
Affinity DataIC50:  20nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552232(CHEMBL4776624)
Affinity DataIC50:  52nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571105(CHEMBL4851375)
Affinity DataIC50:  130nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50130915(CHEBI:3122 | CHEMBL1231178)
Affinity DataIC50:  140nMAssay Description:Inhibition of CE1 in human liver microsomes using 2-(2-Benzoyl-3-methoxyphenyl) benzothiazole as substrate preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552233(CHEMBL4748399)
Affinity DataIC50:  380nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552231(CHEMBL4740149)
Affinity DataIC50:  610nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50556551(CHEMBL4780848)
Affinity DataIC50:  630nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154559(CHEMBL2151605)
Affinity DataIC50:  660nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50556550(CHEMBL4748929)
Affinity DataIC50:  810nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552214(CHEMBL4747287)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552212(CHEMBL4761197)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552215(CHEMBL4751728)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50233165(CHEMBL1222042)
Affinity DataIC50:  1.57E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552229(CHEMBL4752404)
Affinity DataIC50:  1.62E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50556549(CHEMBL4764489)
Affinity DataIC50:  2.81E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552230(CHEMBL4745825)
Affinity DataIC50:  2.86E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552228(CHEMBL4756815)
Affinity DataIC50:  2.91E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154558(CHEMBL3775320)
Affinity DataIC50:  3.42E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50084040(Bavachinin A)
Affinity DataIC50:  3.47E+3nMAssay Description:Inhibition of CE1 in human liver microsomes using 2-(2-Benzoyl-3-methoxyphenyl) benzothiazole as substrate preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571096(CHEMBL4871900)
Affinity DataIC50:  3.82E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154554(CHEMBL3775391)
Affinity DataIC50:  3.95E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154560(CHEMBL3775118)
Affinity DataIC50:  3.99E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50084040(Bavachinin A)
Affinity DataIC50:  4.31E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552232(CHEMBL4776624)
Affinity DataIC50:  4.45E+3nMAssay Description:Inhibition of hCES2A in human HepG2 cells assessed as reduction in fluorogenic substrate NCEN hydrolysis preincubated for 1 hr followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571080(CHEMBL4875001)
Affinity DataIC50:  5.16E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50556547(CHEMBL4759252)
Affinity DataIC50:  5.23E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50058817(CHEMBL1271483)
Affinity DataIC50:  5.61E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154562(CHEMBL1271536)
Affinity DataIC50:  5.70E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552219(CHEMBL4170979)
Affinity DataIC50:  5.94E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50130915(CHEBI:3122 | CHEMBL1231178)
Affinity DataIC50:  6.11E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571094(CHEMBL4864916)
Affinity DataIC50:  6.19E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50130915(CHEBI:3122 | CHEMBL1231178)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571083(CHEMBL4848122)
Affinity DataIC50:  6.68E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50017698(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50346605(CHEMBL487933)
Affinity DataIC50:  6.95E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154555(CHEMBL3775916)
Affinity DataIC50:  6.99E+3nMAssay Description:Inhibition of CE1 in human liver microsomes using 2-(2-Benzoyl-3-methoxyphenyl) benzothiazole as substrate preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571081(CHEMBL4871946)
Affinity DataIC50:  7.11E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154556(CHEMBL1271200)
Affinity DataIC50:  7.36E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571092(CHEMBL4870040)
Affinity DataIC50:  7.76E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571085(CHEMBL4853642)
Affinity DataIC50:  8.24E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571091(CHEMBL4870605)
Affinity DataIC50:  9.04E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571104(CHEMBL4850016)
Affinity DataIC50:  9.12E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154554(CHEMBL3775391)
Affinity DataIC50:  9.13E+3nMAssay Description:Inhibition of CE1 in human liver microsomes using 2-(2-Benzoyl-3-methoxyphenyl) benzothiazole as substrate preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50346605(CHEMBL487933)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of CE1 in human liver microsomes using 2-(2-Benzoyl-3-methoxyphenyl) benzothiazole as substrate preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50556546(CHEMBL4748860)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute Of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571089(CHEMBL4866857)
Affinity DataIC50:  1.09E+4nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 88 total ) | Next | Last >>
Jump to: