BindingDB PrimarySearch

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244449((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...)

Ki: 0.180nMAssay Description:Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Melatonin receptor type 1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50352003(CHEMBL1823015)

Ki: 0.200nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244450((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-2-ylmethyl...)

Ki: 0.200nMAssay Description:Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Melatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50340329(4-azamelatonin | CHEMBL1760944)

Ki: 0.240nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Melatonin receptor type 1A(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)

Ki: 0.25nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair

Purchase ChEBI
CHEMBL DrugBank MCE
KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank

Melatonin receptor type 1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)

Ki: 0.340nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Purchase ChEBI
CHEMBL DrugBank MCE
KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed DrugBank

Melatonin receptor type 1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50340329(4-azamelatonin | CHEMBL1760944)

Ki: 0.360nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50245022((E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-3-ylmethy...)

Ki: 0.520nMAssay Description:Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cellsMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244451((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...)

Ki: 0.700nMAssay Description:Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cellsMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244979((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-2-ylmethyl...)

Ki: 0.720nMAssay Description:Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cellsMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244981((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-3-ylmethyl...)

Ki: 1.60nMAssay Description:Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cellsMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50245020((E)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-2-ylmethy...)

Ki: 1.70nMAssay Description:Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cellsMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244866(CHEMBL511820 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-ni...)

Ki: 1.80nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244416(CHEMBL527875 | rac-(E)-{4-[(3-Bromo-4-fluorophenyl...)

Ki: 2.07nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244416(CHEMBL527875 | rac-(E)-{4-[(3-Bromo-4-fluorophenyl...)

Ki: 2.07nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50245091(CHEMBL519398 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-ni...)

Ki: 2.22nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244865(CHEMBL471153 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-ni...)

Ki: 2.30nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244693(CHEMBL516638 | rac-(E)-{4-[(3-Chloro-4-fluoropheny...)

Ki: 2.45nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244693(CHEMBL516638 | rac-(E)-{4-[(3-Chloro-4-fluoropheny...)

Ki: 2.45nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244961(CHEMBL472520 | rac-(E/Z)-(4-heptylidene-2-(hydroxy...)

Ki: 2.5nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244961(CHEMBL472520 | rac-(E/Z)-(4-heptylidene-2-(hydroxy...)

Ki: 2.5nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244413(CHEMBL488498 | rac-(E)-{4-[(3-Bromo-4-fluorophenyl...)

Ki: 2.66nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244413(CHEMBL488498 | rac-(E)-{4-[(3-Bromo-4-fluorophenyl...)

Ki: 2.66nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244414(CHEMBL488500 | rac-(E)-{4-[(4-Chlorophenyl)methyle...)

Ki: 2.90nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244414(CHEMBL488500 | rac-(E)-{4-[(4-Chlorophenyl)methyle...)

Ki: 2.90nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244648(CHEMBL453598 | rac-(E)-(2-(Hydroxymethyl)-5-oxo-4-...)

Ki: 2.96nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244648(CHEMBL453598 | rac-(E)-(2-(Hydroxymethyl)-5-oxo-4-...)

Ki: 2.96nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50245049(CHEMBL488706 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-ni...)

Ki: 3.10nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244481((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...)

Ki: 3.30nMAssay Description:Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244740(CHEMBL461372 | rac-(E)-{4-[(3-Chloro-4-fluoropheny...)

Ki: 3.38nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244740(CHEMBL461372 | rac-(E)-{4-[(3-Chloro-4-fluoropheny...)

Ki: 3.38nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244908(CHEMBL511301 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-me...)

Ki: 3.70nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244908(CHEMBL511301 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-me...)

Ki: 3.70nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244974((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...)

Ki: 3.70nMAssay Description:Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cellsMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244482((4-(4-nitrobenzylidene)-2-(hydroxymethyl)-5-oxo-te...)

Ki: 3.80nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244482((4-(4-nitrobenzylidene)-2-(hydroxymethyl)-5-oxo-te...)

Ki: 3.80nMAssay Description:Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cellsMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244915(CHEMBL472002 | rac-(E)-{2-(Hydroxymethyl)-4-[(3-ni...)

Ki: 3.90nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50245021((Z)-(2-(hydroxymethyl)-5-oxo-4-(quinolin-2-ylmethy...)

Ki: 4.60nMAssay Description:Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cellsMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Protein kinase C alpha type(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244450((E)-(2-(hydroxymethyl)-5-oxo-4-(pyridin-2-ylmethyl...)

Ki: 4.60nMAssay Description:Displacement of [3H]PDBu from human recombinant PKCalpha expressed in Escherichia coli BL21-21-Gold (DE3)More data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244643(CHEMBL452307 | rac-(E)-(4-{[4-(Dimethylamino)pheny...)

Ki: 4.68nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244863(CHEMBL472362 | rac-(E)-{4-[(4-Chloro-3-fluoropheny...)

Ki: 4.89nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244914(CHEMBL472001 | rac-(E)-{2-(Hydroxymethyl)-4-[(3-ni...)

Ki: 5.30nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244690(CHEMBL358095 | rac-(E)-{4-[(4-Fluorophenyl)methyle...)

Ki: 5.53nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244690(CHEMBL358095 | rac-(E)-{4-[(4-Fluorophenyl)methyle...)

Ki: 5.53nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244452((4-(4-nitrobenzylidene)-2-(hydroxymethyl)-5-oxo-te...)

Ki: 6.70nMAssay Description:Displacement of [3H]PDBu from RasGRP3 (unknown origin) expressed in cellsMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244554(CHEMBL508402 | rac-(E)-{4-[(4-Chloro-3-fluoropheny...)

Ki: 7.90nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Melatonin receptor type 1B(Homo sapiens (Human))
Universit£

Curated by ChEMBL

BDBM50352005(CHEMBL1823017)

Ki: 8nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in human HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair

Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Ras guanyl-releasing protein 3(Homo sapiens (Human))
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244867(CHEMBL472171 | rac-(E)-{2-(Hydroxymethyl)-4-[(3-ni...)

Ki: 8nMAssay Description:Binding affinity to RasGRP3 (unknown origin)More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Protein kinase C alpha type(MOUSE)
National Cancer Institute-Frederick

Curated by ChEMBL

BDBM50244909(CHEMBL471137 | rac-(E)-{2-(Hydroxymethyl)-4-[(4-me...)

Ki: 8nMAssay Description:Displacement of [3H]PDBu form mouse PKCalpha by scintillation countingMore data for this Ligand-Target Pair