Compile Data Set for Download or QSAR
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Found 96 with Last Name = 'zweerink' and Initial = 'h'
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187039(1-(3,4-dichlorobenzyl)-5-hydroxy-1H-indole-2-carbo...)
Affinity DataKi:  29nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091438((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-1H-...)
Affinity DataKi:  50nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198149((S)-1-(4-(1-(3,5-bis(trifluoromethyl)benzylamino)-...)
Affinity DataIC50:  0.430nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198115(CHEMBL438304 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  0.600nMAssay Description:Inhibition of MCP1-stimulated chemotaxis in monocytes transfected with human CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198109((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-acetam...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of MCP1-stimulated chemotaxis in monocytes transfected with human CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198129(CHEMBL388487 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of MCP1-stimulated chemotaxis in monocytes transfected with human CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198142((2S)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-2-...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198150(CHEMBL397749 | N-(3,5-bis-trifluoromethyl-benzyl)-...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198121(2-(2-amino-1,3-thiazol-4-yl)-N-{[3,5-bis(trifluoro...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198118((2S)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-2-...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198129(CHEMBL388487 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  1.70nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198109((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-acetam...)
Affinity DataIC50:  1.80nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198149((S)-1-(4-(1-(3,5-bis(trifluoromethyl)benzylamino)-...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of MCP1-stimulated chemotaxis in monocytes transfected with human CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198141(CHEMBL230790 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  1.80nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198131(3-(4-(1-(3,5-bis(trifluoromethyl)benzylamino)-1-ox...)
Affinity DataIC50:  2.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198125(CHEMBL387583 | methyl 4-(1-(3,5-bis(trifluoromethy...)
Affinity DataIC50:  2.60nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198115(CHEMBL438304 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198140(1-(4-(1-(3,5-bis(trifluoromethyl)benzylamino)-1-ox...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198130(4-(4-(1H-benzo[d]imidazol-1-yl)piperidin-1-yl)-N-(...)
Affinity DataIC50:  3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198126(CHEMBL230684 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  3.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198123((S)-methyl 4-(1-(3,5-bis(trifluoromethyl)benzylami...)
Affinity DataIC50:  3.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198145(CHEMBL230794 | N-(4-(1-(3,5-bis(trifluoromethyl)be...)
Affinity DataIC50:  3.90nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198124(CHEMBL397747 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198137(CHEMBL389888 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  5.20nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198118((2S)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-2-...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of MCP1-stimulated chemotaxis in monocytes transfected with human CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198146((2R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-2-...)
Affinity DataIC50:  5.80nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198112((2R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-2-...)
Affinity DataIC50:  6.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198122(2-(2-amino-1,3-thiazol-4-yl)-N-{[3,5-bis(trifluoro...)
Affinity DataIC50:  7.30nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198151(CHEMBL395721 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  7.40nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187051((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-((3-(dime...)
Affinity DataIC50:  8nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198108(CHEMBL230727 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  9.10nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187050((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(3-(dimet...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187046((S)-N-(3,5-bis(trifluoromethyl)benzyl)-5-(dimethyl...)
Affinity DataIC50:  13nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198117(CHEMBL231252 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  13nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198119(CHEMBL231340 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  13nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198135((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-aminot...)
Affinity DataIC50:  13.3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198120((R)-tert-butyl 4-(1-(3,5-bis(trifluoromethyl)benzy...)
Affinity DataIC50:  13.3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198111(CHEMBL231149 | N-{4-[1-({[3,5-bis(trifluoromethyl)...)
Affinity DataIC50:  14nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198133((S)-tert-butyl 4-(1-(3,5-bis(trifluoromethyl)benzy...)
Affinity DataIC50:  14.3nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198143(CHEMBL438514 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  14.5nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198132(CHEMBL230165 | N-(4-(1-(3,5-bis(trifluoromethyl)be...)
Affinity DataIC50:  16nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198110(CHEMBL388869 | N-{4-[1-({[3,5-bis(trifluoromethyl)...)
Affinity DataIC50:  17nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198127(CHEMBL396101 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  18nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198116(CHEMBL438128 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  19nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198136(CHEMBL230624 | N-(3,5-bis(trifluoromethyl)benzyl)-...)
Affinity DataIC50:  20nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198134(CHEMBL395289 | N-{[3,5-bis(trifluoromethyl)phenyl]...)
Affinity DataIC50:  23nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187047((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(dimet...)
Affinity DataIC50:  25nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198112((2R)-N-{[3,5-bis(trifluoromethyl)phenyl]methyl}-2-...)
Affinity DataIC50:  27nMAssay Description:Inhibition of MCP1-stimulated chemotaxis in monocytes transfected with human CCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50198128(4-(4-(1H-benzo[d]imidazol-1-yl)piperidin-1-yl)-N-(...)
Affinity DataIC50:  28.6nMAssay Description:Displacement of [125I]MCP1 from human CCR2 expressed in monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50187033((S)-N-(3,5-bis(trifluoromethyl)benzyl)-2-(2-(piper...)
Affinity DataIC50:  30nMAssay Description:Binding affinity to CCR2 in human monocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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