Affinity DataKi: 7nM ΔG°: -48.4kJ/mole IC50: 1.24nMpH: 5.2 T: 2°CAssay Description:Enzymatic activity assay using fluorescent activity-based labeling method.More data for this Ligand-Target Pair
Affinity DataKi: 8nM ΔG°: -48.1kJ/mole IC50: 1.94nMpH: 5.2 T: 2°CAssay Description:Enzymatic activity assay using fluorescent activity-based labeling method.More data for this Ligand-Target Pair
Affinity DataKi: 44nM ΔG°: -43.7kJ/mole IC50: 120nMpH: 5.2 T: 2°CAssay Description:Enzymatic activity assay using fluorescent activity-based labeling method.More data for this Ligand-Target Pair
Affinity DataKi: 93nMAssay Description:Affinity tested by in vitro competition assay of [125I]ASOR binding to parenchymal rat liver cellsMore data for this Ligand-Target Pair
Affinity DataKi: 93nMAssay Description:Affinity tested by in vitro competition assay of [125I]ASOR binding to parenchymal rat liver cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 140nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 152nM ΔG°: -40.5kJ/mole IC50: 150nMpH: 5.2 T: 2°CAssay Description:Enzymatic activity assay using fluorescent activity-based labeling method.More data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 170nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Affinity tested by in vitro competition assay of [125I]ASOR binding to parenchymal rat liver cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 260nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 380nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 400nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 480nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 510nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 530nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 580nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 600nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 620nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 700nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 720nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 740nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 770nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 820nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 840nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 850nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 930nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 930nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 2.20E+3nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 3.00E+3nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 3.30E+3nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Leiden University
Curated by ChEMBL
Leiden University
Curated by ChEMBL
Affinity DataKi: 5.30E+3nMAssay Description:Displacement of [125I]triptorelin from human GnRHR expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 5.30E+4nM ΔG°: -25.4kJ/mole IC50: 9.49E+3nMpH: 5.2 T: 2°CAssay Description:Enzymatic activity assay using fluorescent activity-based labeling method.More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.0800nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.120nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.400nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of glucosylceramidase 2 from spleen of patient with gaucher's disease by fluorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of GBA2 (unknown origin)More data for this Ligand-Target Pair