Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetNatural resistance-associated macrophage protein 2(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL

LigandBDBM50361140(CHEMBL1933615)Copy SMILESCopy InChI

Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching methodMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetLysine-specific demethylase 4E(Homo sapiens (Human))
Max Delbr�Ck Center For Molecular Medicine In The Helmholtz Gemeinschaft (Mdc)

Curated by ChEMBL

LigandBDBM50361140(CHEMBL1933615)Copy SMILESCopy InChI

Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 preincubated for 10 mins ...More data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI