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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetNatural resistance-associated macrophage protein 2(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50361146(CHEMBL1933775)
Affinity DataIC50:  520nMAssay Description:Inhibition of human DMT1 expressed in CHO cells assessed as blockage of ferrous influx after 20 mins by calcein fluorescence quenching methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4E(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50361146(CHEMBL1933775)
Affinity DataIC50:  900nMAssay Description:Inhibition of N-terminal His6-tagged human KDM4E (1 to 337 residues) catalytic domain measured formaldehyde dehydrogenase (FDH)-coupled fluorescence ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific demethylase 4E(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50361146(CHEMBL1933775)
Affinity DataIC50:  900nMAssay Description:Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 preincubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4E(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50361146(CHEMBL1933775)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 preincubated for 10 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed