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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetNatural resistance-associated macrophage protein 2(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50387726(CHEMBL2058878)
Affinity DataKi:  1.40E+3nMAssay Description:Competitive inhibition of human DMT1 expressed in HEK293T cells by measuring inhibition of radiolabeled-55Fe2+ uptake by Dixon plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNatural resistance-associated macrophage protein 2(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50387726(CHEMBL2058878)
Affinity DataIC50:  140nMAssay Description:Inhibition of human DMT1 expressed in Xenopus oocytes assessed as inhibition of channel currents at -50 mV holding potential by two-electrode voltage...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNatural resistance-associated macrophage protein 2(Homo sapiens (Human))
University Of Bern

Curated by ChEMBL
LigandPNGBDBM50387726(CHEMBL2058878)
Affinity DataIC50:  1.76E+3nMAssay Description:Inhibition of human DMT1 expressed in HEK293T cells assessed as inhibition of radiolabeled 55Fe2+ uptake preincubated with compound for 5 mins follow...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNatural resistance-associated macrophage protein 1(Homo sapiens (Human))
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50387726(CHEMBL2058878)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of NRAMP1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed