Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetAcrosin(Sus scrofa)
TBA

Curated by ChEMBL

LigandBDBM50010136(CHEMBL3245422)Copy SMILESCopy InChI

Affinity DataKi:  210nMAssay Description:Reversible competitive inhibition of boar spermatozoa acrosin using BzArgOEt as substrate by Dixon plot analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetProthrombin(Bos taurus (Bovine))
TBA

Curated by ChEMBL

LigandBDBM50010136(CHEMBL3245422)Copy SMILESCopy InChI

Affinity DataKi:  270nMAssay Description:Inhibition of amidase activity of bovine thrombin using BPVANA as substrate after 15 to 40 minsMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetGlandular kallikrein(Sus scrofa)
TBA

Curated by ChEMBL

LigandBDBM50010136(CHEMBL3245422)Copy SMILESCopy InChI

Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of porcine pancreatic kallikrein using BANA as substrate after 15 to 180 minsMore data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetProthrombin(Homo sapiens (Human))
TBA

Curated by ChEMBL

LigandBDBM50010136(CHEMBL3245422)Copy SMILESCopy InChI

Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of human thrombin-mediated blood clotting formation in presence of human fibrinogenMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI