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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetPhospholipase A2, membrane associated(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50242184(Scalaradial)
Affinity DataIC50:  15nMAssay Description:In vitro inhibitory activity against human synovial fluid phospholipase A2 (HSF-PLA2) by monitoring hydrolysis of [3H]-arachidonic acid labeled E. co...More data for this Ligand-Target Pair
In DepthDetails Article
TargetPhospholipase A2(Apis mellifera)
Queen'S Center For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50242184(Scalaradial)
Affinity DataIC50:  70nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Apis mellifera)
Queen'S Center For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50242184(Scalaradial)
Affinity DataIC50:  70nMAssay Description:Inhibition of bee venom PLA2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50242184(Scalaradial)
Affinity DataIC50:  210nMAssay Description:Inhibition of human TRPM2 expressed in HEK293T cells assessed as blocked of ADPR-activated current by whole cell patch clamp electrophysiologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Homo sapiens (Human))
Peking University

Curated by ChEMBL
LigandPNGBDBM50242184(Scalaradial)
Affinity DataIC50:  210nMAssay Description:Inhibition of human FLAG-tagged TRPM2 expressed in HEK293 cells assessed as reduction in ADPR-induced intracellular calcium flux after 30 to 60 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 2(Rattus norvegicus)
Queen'S Center For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50242184(Scalaradial)
Affinity DataIC50:  330nMAssay Description:Inhibition of TRPM2 in rat INS-1 cells assessed as reduction in ADPR-induced intracellular calcium flux measured after 60 mins by whole cell patch cl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily M member 7(Mus musculus)
Queen'S Center For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50242184(Scalaradial)
Affinity DataIC50:  760nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed