Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
New York University Medical Center

Curated by ChEMBL

LigandBDBM50471702(CHEMBL88448)Copy SMILESCopy InChI

Affinity DataKi:  20nMAssay Description:Binding affinity determined by displacement of [3H]prazosin from alpha-1A adrenergic receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
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TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
New York University Medical Center

Curated by ChEMBL

LigandBDBM50471702(CHEMBL88448)Copy SMILESCopy InChI

Affinity DataKi:  240nMAssay Description:Binding affinity determined by displacement of [3H]prazosin from alpha-1B adrenergic receptorMore data for this Ligand-Target Pair

Target InfoReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
New York University Medical Center

Curated by ChEMBL

LigandBDBM50471702(CHEMBL88448)Copy SMILESCopy InChI

Affinity DataKi:  245nMAssay Description:Binding affinity assayed by displacement of [3H]rauwolscine from human alpha-2C adrenergic receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
New York University Medical Center

Curated by ChEMBL

LigandBDBM50471702(CHEMBL88448)Copy SMILESCopy InChI

Affinity DataKi:  490nMAssay Description:Binding affinity determined by displacement of [3H]rauwolscine from alpha-2B adrenergic receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
New York University Medical Center

Curated by ChEMBL

LigandBDBM50471702(CHEMBL88448)Copy SMILESCopy InChI

Affinity DataKi:  501nMAssay Description:Binding affinity determined by displacement of [3H]prazosin from alpha-1D adrenergic receptorMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
New York University Medical Center

Curated by ChEMBL

LigandBDBM50471702(CHEMBL88448)Copy SMILESCopy InChI

Affinity DataKi:  676nMAssay Description:Binding affinity determined by displacement of [3H]rauwolscine from alpha-2A adrenergic receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetVoltage-dependent L-type calcium channel subunit alpha-1S(Rattus norvegicus)
New York University Medical Center

Curated by ChEMBL

LigandBDBM50471702(CHEMBL88448)Copy SMILESCopy InChI

Affinity DataKi: <1.00E+3nMAssay Description:Binding affinity at the L-type [Ca2+] channel from rat brain homogenate by [3H]nitrendipine displacement.More data for this Ligand-Target Pair

Target InfoPDBMMDB
UniProtKB/SwissProt
B.MOADGoogleScholar

Ligand InfoPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI