Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 5 hits in this display   

TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50317048(CHEMBL1097342 | N-((1S,2S)-3-(3,5-difluorophenyl)-...)
Affinity DataKi:  0.800nMAssay Description:Inhibition oh BACE1More data for this Ligand-Target Pair
TargetBeta-secretase 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50317048(CHEMBL1097342 | N-((1S,2S)-3-(3,5-difluorophenyl)-...)
Affinity DataKi:  5.40nMAssay Description:Inhibition oh BACE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin E(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50317048(CHEMBL1097342 | N-((1S,2S)-3-(3,5-difluorophenyl)-...)
Affinity DataKi:  86nMAssay Description:Inhibition oh cathepsin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin D(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50317048(CHEMBL1097342 | N-((1S,2S)-3-(3,5-difluorophenyl)-...)
Affinity DataKi:  200nMAssay Description:Inhibition oh cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50317048(CHEMBL1097342 | N-((1S,2S)-3-(3,5-difluorophenyl)-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of BACE1 expressed in HEK293 cells expressing human APP assessed as amyloid beta42 productionMore data for this Ligand-Target Pair