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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
14
hits in this display
Target
Nucleotide-binding oligomerization domain-containing protein 2
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM50227494
(CHEMBL257286 | N-(quinolin-8-yl)benzenesulfonamide...)
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Affinity Data
IC50: 1.83E+3nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
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Target
Tumor necrosis factor
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM50227494
(CHEMBL257286 | N-(quinolin-8-yl)benzenesulfonamide...)
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Affinity Data
IC50: 2.74E+3nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
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Target
Type-1 angiotensin II receptor
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM50227494
(CHEMBL257286 | N-(quinolin-8-yl)benzenesulfonamide...)
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Affinity Data
IC50: 2.75E+3nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, C...
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Target
Endothelial PAS domain-containing protein 1
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM50227494
(CHEMBL257286 | N-(quinolin-8-yl)benzenesulfonamide...)
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Affinity Data
IC50: 3.37E+3nM
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Target
Lactoylglutathione lyase
(Homo sapiens (Human))
TBA
Curated by
ChEMBL
Ligand
BDBM50227494
(CHEMBL257286 | N-(quinolin-8-yl)benzenesulfonamide...)
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Affinity Data
IC50: 8.50E+3nM
Assay Description:
Inhibition recombinant human N-terminal 6His-tagged GLO1 (2 to 184 residues) expressed in Escherichia coli using MG as substrate preincubated for 15 ...
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Target
Transcription factor p65
(Homo sapiens (Human))
Columbia University
Curated by
ChEMBL
Ligand
BDBM50227494
(CHEMBL257286 | N-(quinolin-8-yl)benzenesulfonamide...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC
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Target
Apelin receptor
(Homo sapiens (Human))
Sanford-Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM50227494
(CHEMBL257286 | N-(quinolin-8-yl)benzenesulfonamide...)
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Affinity Data
IC50: 3.55E+4nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford- Sanford-Burnham Medical Research Institute(SBMRI, San...
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Target
Methionine aminopeptidase 2
(Homo sapiens (Human))
Universit£T Heidelberg
Curated by
ChEMBL
Ligand
BDBM50227494
(CHEMBL257286 | N-(quinolin-8-yl)benzenesulfonamide...)
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Affinity Data
IC50: 3.98E+4nM
Assay Description:
Inhibition of human MetAP2 expressed in baculovirus infected Sf9 cells
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Target
Methionine aminopeptidase 1
(Homo sapiens (Human))
Universit£T Heidelberg
Curated by
ChEMBL
Ligand
BDBM50227494
(CHEMBL257286 | N-(quinolin-8-yl)benzenesulfonamide...)
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Affinity Data
IC50: 4.49E+4nM
Assay Description:
Inhibition of human MetAP1
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Target
Beta-glucuronidase
(Bos taurus (Bovine))
University Of Karachi
Curated by
ChEMBL
Ligand
BDBM50227494
(CHEMBL257286 | N-(quinolin-8-yl)benzenesulfonamide...)
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Affinity Data
IC50: 6.64E+4nM
Assay Description:
Antagonistic activity for inhibition of histamine H2 receptor from anesthetized rats
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Target
NF-kappa-B inhibitor alpha
(Homo sapiens (Human))
Columbia University
Curated by
ChEMBL
Ligand
BDBM50227494
(CHEMBL257286 | N-(quinolin-8-yl)benzenesulfonamide...)
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Affinity Data
EC50: 2.00E+4nM
Assay Description:
Induction of human IkappaBalpha stabilization in OCI-Ly3 cells assessed as ratio of green light emiting IkappaBalpha-fused luciferase expression to r...
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Target
Nucleotide-binding oligomerization domain-containing protein 1
(Homo sapiens (Human))
Burnham Center For Chemical Genomics
Curated by
PubChem BioAssay
Ligand
BDBM50227494
(CHEMBL257286 | N-(quinolin-8-yl)benzenesulfonamide...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 2.00E+4nM
Assay Description:
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
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Target
Streptokinase A
(Streptococcus pyogenes M1 GAS)
Broad Institute
Curated by
PubChem BioAssay
Ligand
BDBM50227494
(CHEMBL257286 | N-(quinolin-8-yl)benzenesulfonamide...)
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Affinity Data
EC50: 1.50E+5nM
Assay Description:
Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...
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Target
NF-kappa-B inhibitor alpha
(Homo sapiens (Human))
Columbia University
Curated by
ChEMBL
Ligand
BDBM50227494
(CHEMBL257286 | N-(quinolin-8-yl)benzenesulfonamide...)
Copy SMILES
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Affinity Data
EC50: 1.70E+4nM
Assay Description:
Induction of human IkappaBalpha stabilization in OCI-Ly3 cells by green light emiting IkappaBalpha-fused luciferase reporter gene assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
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antibodypedia
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CHEMBL
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Article
PubMed
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