TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 0.620nMAssay Description:Inhibition of uPA (unknown origin)More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:The compound was tested in vitro for its inhibitory activity against human urokinase enzyme, activity expressed as IC50More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 5.10nMAssay Description:The compound was tested in vitro for its inhibitory activity against human urokinase enzyme, activity expressed as IC50More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 6.60nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of [3H]-FPP incorporation into biotin-linked K-ras decapeptide (CVIM) by bovine farnesyltransferaseMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 10nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:The compound was tested in vitro for its inhibitory activity against human urokinase enzyme, activity expressed as IC50More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:The compound was tested in vitro for its inhibitory activity against human urokinase enzyme, activity expressed as IC50More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:The compound was tested in vitro for its inhibitory activity against human urokinase enzyme, activity expressed as IC50More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 14nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human urokinase using fluorescent peptide as substrate by florescence assayMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:The compound was tested in vitro for its inhibitory activity against human urokinase enzyme, activity expressed as IC50More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human uPA using fluorescent peptide as substrate by florescence assayMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of human uPA using fluorescent peptide as substrate by florescence assayMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 20nMpH: 7.8 T: 2°CAssay Description:Enzyme activity assay using human and murine PAI-1.More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:The compound was tested in vitro for its inhibitory activity against human urokinase enzyme, activity expressed as IC50More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of human uPA by chromogenic assay using Cbz-Val-Gly-Arg-pNA as chromogenic substrateMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 26.5nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetPlasminogen activator inhibitor 1/Urokinase-type plasminogen activator(Homo sapiens (Human))
University of Michigan
US Patent
University of Michigan
US Patent
Affinity DataIC50: 33nMpH: 7.4 T: 2°CAssay Description:To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...More data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Wollongong
Curated by ChEMBL
University of Wollongong
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair