Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Upjohn Laboratories
Curated by ChEMBL
Upjohn Laboratories
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Tested for its inhibitory activity against HMG-CoA reductase transcription in HepG2 cellsMore data for this Ligand-Target Pair
TargetSterol regulatory element-binding protein 2(Homo sapiens (Human))
Kyoto University
Curated by ChEMBL
Kyoto University
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells cotransfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after 2...More data for this Ligand-Target Pair