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Found 7 of ic50 for monomerid = 253994
TargetBaculoviral IAP repeat-containing protein 2 [256-363](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM253994(US9481673, (S)-4)
Affinity DataIC50:  1nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM253994(US9481673, (S)-4)
Affinity DataIC50:  303nMT: 2°CAssay Description:BIR3 domains (10 nM) were incubated with SMAC peptide (10 nM) in assay buffer (50 mM Tris, 120 mM NaCl, 0.1% BSA, 1 mM DTT, 0.05% Triton X100) for on...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2D6(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM253994(US9481673, (S)-4)
Affinity DataIC50:  6.40E+3nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 2C8(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM253994(US9481673, (S)-4)
Affinity DataIC50:  9.80E+3nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetCytochrome P450 2C9(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM253994(US9481673, (S)-4)
Affinity DataIC50:  2.70E+4nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
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TargetCytochrome P450 2C19(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM253994(US9481673, (S)-4)
Affinity DataIC50:  3.60E+4nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM253994(US9481673, (S)-4)
Affinity DataIC50: >5.00E+4nMAssay Description:The final incubation volume contains TRIS buffer (0.1 M), MgCl2 (5 mM), a certain concentration of human liver microsomes dependent on the P450 isoen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent