Compile Data Set for Download or QSAR
maximum 50k data
Found 25 of ic50 for monomerid = 29608
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50:  4.90nMAssay Description:Binding affinity to human ERRgammaMore data for this Ligand-Target Pair
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Kyushu University

Curated by ChEMBL
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50:  13.1nMpH: 7.4 T: 2°CAssay Description:The receptor-binding assay was conducted using [3H]4-hydroxytamoxifen (4-OHT) as the radioligand. To estimate the binding affinity, the IC50 values (...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Sabic Global Technologies

US Patent
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50:  490nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Sabic Global Technologies

US Patent
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50:  504nMAssay Description:Binding affinity to GST-tagged human ER alpha ligand-binding domain by TR-FRET assayMore data for this Ligand-Target Pair
TargetEstrogen receptor beta(Homo sapiens (Human))
Sabic Global Technologies

US Patent
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50:  670nMAssay Description:Competitive binding assays were performed by incubating rhER alpha (α) and beta 1 (β1) receptors with 10 nM [3H]estradiol (the radio ligand...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen receptor beta(Homo sapiens (Human))
Sabic Global Technologies

US Patent
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50:  870nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERbeta ligand binding domain expressed in Escherichia coli BL21alpha cells inc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Sabic Global Technologies

US Patent
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50:  904nMAssay Description:Displacement of [3H]17-beta estradiol from GST-fused human recombinant ERalpha ligand binding domain expressed in Escherichia coli BL21alpha cells in...More data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
University of Chemistry and Technology Prague

Curated by ChEMBL
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of rabbit skeletal muscle microsomes SERCA1a by enzyme-coupled methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 2(Rattus norvegicus)
University of Chemistry and Technology Prague

Curated by ChEMBL
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of rat cerebellar microsomes SERCA2b by enzyme-coupled methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50:  5.90E+3nMAssay Description:Antagonist activity at human pSG5-AR assessed as inhibition of dihydrotestosterone-induced effect by reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Sabic Global Technologies

US Patent
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at FLAG-tagged ERalpha (unknown origin) expressed in HEK293 cells assessed as reduction in E2-induced ER-alpha-mediated transcrip...More data for this Ligand-Target Pair
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human DYRK4 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scint...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))TBA
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human GSK-3beta expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric s...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human CDK5/p25 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric sc...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))TBA
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human CK1epsilon expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))TBA
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human CLK1 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scinti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK2(Homo sapiens (Human))TBA
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human CLK2 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scinti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK3(Homo sapiens (Human))TBA
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human CLK3 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scinti...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))TBA
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human CLK4 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scinti...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human DYRK1A expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scin...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human DYRK1B expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scin...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human DYRK2 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scint...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human DYRK3 expressed in Sf9 insect cells incubated for 60 mins in presence of ATP and [gamma33-P] ATP by radiometric scint...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50:  7.41E+4nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
University of Chemistry and Technology Prague

Curated by ChEMBL
LigandPNGBDBM29608(Bisphenol A (BPA) | Diphenylolpropane | US9688816,...)
Affinity DataIC50:  2.33E+5nMAssay Description:Inhibition of rabbit microsomes SERCA1a by enzyme-coupled methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed