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Found 9 of ic50 for monomerid = 474222
TargetAdenosine receptor A1(Homo sapiens (Human))
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM474222(5-(5-amino-2-(2,6-difluorobenzyl)-7-(4- fluorophen...)
Affinity DataIC50:  0.200nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM474222(5-(5-amino-2-(2,6-difluorobenzyl)-7-(4- fluorophen...)
Affinity DataIC50:  0.200nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM474222(5-(5-amino-2-(2,6-difluorobenzyl)-7-(4- fluorophen...)
Affinity DataIC50:  0.600nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
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TargetAdenosine receptor A2a(Mus musculus)
TBA

US Patent
LigandPNGBDBM474222(5-(5-amino-2-(2,6-difluorobenzyl)-7-(4- fluorophen...)
Affinity DataIC50:  0.800nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM474222(5-(5-amino-2-(2,6-difluorobenzyl)-7-(4- fluorophen...)
Affinity DataIC50:  2.10nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM474222(5-(5-amino-2-(2,6-difluorobenzyl)-7-(4- fluorophen...)
Affinity DataIC50:  2.10nMAssay Description:Binding affinity and specificities of the compounds against different subtype of human adenosine receptors (hA1, hA2A, hA2B and hA3) were characteriz...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM474222(5-(5-amino-2-(2,6-difluorobenzyl)-7-(4- fluorophen...)
Affinity DataIC50:  20nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
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TargetAdenosine receptor A2b(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM474222(5-(5-amino-2-(2,6-difluorobenzyl)-7-(4- fluorophen...)
Affinity DataIC50:  56nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
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TargetAdenosine receptor A3(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM474222(5-(5-amino-2-(2,6-difluorobenzyl)-7-(4- fluorophen...)
Affinity DataIC50: >1.00E+4nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent