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Found 4 of ic50 for monomerid = 50062249
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50062249(CHEMBL285434 | trisodium 5-[2-benzo[d][1,3]dioxol-...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Farnesyltransferase from rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50062249(CHEMBL285434 | trisodium 5-[2-benzo[d][1,3]dioxol-...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of Farnesyltransferase in competitive manner with respect to FPP (farnesyl diphosphate) at 0.6 microM FPP and 0.36 microM Ras peptideMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50062249(CHEMBL285434 | trisodium 5-[2-benzo[d][1,3]dioxol-...)
Affinity DataIC50:  7.20nMAssay Description:Inhibition of Farnesyltransferase in competitive manner with respect to FPP (farnesyl diphosphate) at 0.6 microM FPP and 3.6 microM Ras peptide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Rattus norvegicus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50062249(CHEMBL285434 | trisodium 5-[2-benzo[d][1,3]dioxol-...)
Affinity DataIC50:  45nMAssay Description:Inhibition of FTase in competitive manner with respect to FPP (farnesyl diphosphate) at 6.0 microM FPP and 0.36 microM Ras peptide.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed