Affinity DataIC50: 23nMAssay Description:Inhibition of human NHE3 expressed in LAP1 cell assessed as intracellular pH recovery measured for 2 mins by CECF-AM dye based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 in pooled human hepatic microsomes using dextromethorphan substrate in presence of NADPHMore data for this Ligand-Target Pair