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Found 9 of ic50 for monomerid = 6497
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth-Ayerst Research

LigandPNGBDBM6497(6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinazolin...)
Affinity DataIC50:  280nMpH: 7.5 T: 2°CAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-G-associated kinase(Homo sapiens (Human))
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM6497(6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinazolin...)
Affinity DataIC50:  350nMAssay Description:Inhibition of tracer 5 binding to human N-terminal nano luciferase-fused GAK expressed in HEK293 cells measured after 2 hrs by nanoBRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM6497(6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinazolin...)
Affinity DataIC50:  500nMAssay Description:Antagonism towards Epidermal growth factor receptorMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM6497(6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinazolin...)
Affinity DataIC50:  500nMAssay Description:Inhibition of p56 lck tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM6497(6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinazolin...)
Affinity DataIC50:  500nMAssay Description:Inhibition of p56lck kinase autophosphorylation in Jurkat cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM6497(6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinazolin...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM6497(6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinazolin...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of EGFR in human A431 cells assessed as reduction in EGF-stimulated EGFR autophosphorylation preincuabted for 90 mins followed by EGF-stim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM6497(6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinazolin...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of platelet-derived growth factor receptor (PDGF-R)More data for this Ligand-Target Pair
In DepthDetails Article
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM6497(6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinazolin...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonism towards Colony stimulating factor 1 receptor (CSF-1R)More data for this Ligand-Target Pair
In DepthDetails Article