TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of EAAT2 (unknown origin) transiently expressed in COS1 cells by [14C]glutamate based uptake assayMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human GLT1 expressed in Xenopus laevis Oocytes assessed as reduction of [3H]-glutamate uptake after 10 mins by scintillation countingMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 47nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 85nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 107nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration against glutamate uptake in oocytes expressing in human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 209nMAssay Description:Inhibition of human EAAT2 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of human EAAT2 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 309nMAssay Description:Inhibition of human EAAT2 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of human EAAT2 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 501nMAssay Description:Inhibition of [3H]-D-Asp uptake at human EAAT2 expressed in HEK293 cells measured after 3 mins by TopCount methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration against glutamate uptake in HEK cells expressing human Excitatory amino acid transporter 2More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 690nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
University of Groningen
Curated by ChEMBL
University of Groningen
Curated by ChEMBL
Affinity DataIC50: 692nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as reduction in [3H]-D-Asp uptake incubated for 4 mins by scintillation counting methodMore data for this Ligand-Target Pair