Compile Data Set for Download or QSAR
maximum 50k data
Found 83 of ic50 for UniProtKB: Q14534
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032836(4-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032836(4-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032850(CHEMBL27885 | [3-([3,3']Bithiophenyl-5-ylmethoxy)-...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032843(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032853(2-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032843(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50:  30nMAssay Description:Compound was evaluated for the inhibition of pig liver microsomal squalene epoxidase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070340(CHEMBL281025 | Thiophene-2-sulfonic acid [2-(3-{[(...)
Affinity DataIC50:  50nMAssay Description:Compound was evaluated in vitro for the inhibition of pig liver squalene epoxidase in HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032856(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-(3-{[(4-...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070340(CHEMBL281025 | Thiophene-2-sulfonic acid [2-(3-{[(...)
Affinity DataIC50:  60nMAssay Description:Compound was evaluated for inhibitory activity against cholesteryl ester transfer proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032837(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-(3-{[dimethyl-...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032847(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-(3-{[dimethyl-...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032830(CHEMBL107568 | {3-[(Dimethyl-o-tolyl-silanyl)-meth...)
Affinity DataIC50:  70nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070340(CHEMBL281025 | Thiophene-2-sulfonic acid [2-(3-{[(...)
Affinity DataIC50:  80nMAssay Description:Compound was evaluated for inhibitory activity against cholesteryl ester transfer protein, reported from fungusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070337(CHEMBL27154 | [3,3']Bithiophenyl-5-sulfonic acid [...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032848((6,6-Dimethyl-hepta-2,4-diynyl)-{3-[(dimethyl-o-to...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070344(CHEMBL26950 | Thiophene-2-sulfonic acid [2-(3-{[((...)
Affinity DataIC50:  90nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291660(CHEMBL16178 | [3-([3,3']Bithiophenyl-5-ylmethoxy)-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032834(4-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288841((3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-ami...)
Affinity DataIC50:  100nMAssay Description:Compound was evaluated for the inhibition of pig liver microsomal squalene epoxidase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032832(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50:  120nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032842(CHEMBL108144 | {3-[(Benzyl-dimethyl-silanyl)-metho...)
Affinity DataIC50:  130nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032844(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032840(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-(3-{[(2-...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070341(CHEMBL26151 | Pyridine-3-sulfonic acid [2-(3-{[((E...)
Affinity DataIC50:  150nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070343(CHEMBL26596 | Thiazole-2-sulfonic acid [2-(3-{[((E...)
Affinity DataIC50:  170nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070345(CHEMBL26964 | Thiophene-2-sulfonic acid [2-(3-{[((...)
Affinity DataIC50:  170nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070331(4-Cyano-N-[2-(3-{[((E)-6,6-dimethyl-hept-2-en-4-yn...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070350(CHEMBL284197 | N-[2-(3-{[((E)-6,6-Dimethyl-hept-2-...)
Affinity DataIC50:  200nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032835((3-{[(4-Bromo-phenyl)-dimethyl-silanyl]-methoxy}-b...)
Affinity DataIC50:  210nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070346(CHEMBL27941 | [2,3']Bithiophenyl-5-sulfonic acid [...)
Affinity DataIC50:  210nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070342(CHEMBL26077 | Thiophene-2-sulfonic acid cyclopropy...)
Affinity DataIC50:  230nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070349(CHEMBL26597 | Thiophene-3-sulfonic acid [2-(3-{[((...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070333(CHEMBL281666 | N-[2-(3-{[((E)-6,6-Dimethyl-hept-2-...)
Affinity DataIC50:  255nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291661(CHEMBL267332 | [3-(3-Azido-phenyl)-prop-2-ynyl]-[3...)
Affinity DataIC50:  270nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070348(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-{3-[3-(t...)
Affinity DataIC50:  290nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070339(4-Bromo-thiophene-2-sulfonic acid [2-(3-{[((E)-6,6...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070347(4-Bromo-N-[2-(3-{[((E)-6,6-dimethyl-hept-2-en-4-yn...)
Affinity DataIC50:  330nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070338(5-Bromo-thiophene-2-sulfonic acid [2-(3-{[((E)-6,6...)
Affinity DataIC50:  390nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032831((3-{[(4-Chloro-phenyl)-dimethyl-silanyl]-methoxy}-...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070335(CHEMBL280972 | Thiophene-2-sulfonic acid [2-(3-{[(...)
Affinity DataIC50:  450nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291658((3-{[(4-Azido-phenyl)-dimethyl-silanyl]-methoxy}-b...)
Affinity DataIC50:  520nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032851(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-(3-{[(4-...)
Affinity DataIC50:  870nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291659(CHEMBL16120 | [3-(4-Azido-phenyl)-prop-2-ynyl]-[3-...)
Affinity DataIC50:  960nMAssay Description:In vitro inhibition of pig liver microsomal squalene epoxidase (SE) by measuring the extend of cholesterol radiolabeling after incubation with [14C]-...More data for this Ligand-Target Pair
In DepthDetails Article
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032833(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-ethyl-(3-{[(4-...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032839(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-(3-{[dimethyl-...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50070334(Benzo[b]thiophene-2-sulfonic acid [2-(3-{[((E)-6,6...)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro inhibition of cholesterol biosynthesis in human HepG2 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032854(((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-{3-[(dimethyl-...)
Affinity DataIC50:  3.00E+3nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015507(4,8,13,17,21-Pentamethyl-docosa-4,8,12,16,20-penta...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of pig liver squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50015503(5,9,14,18,22-Pentamethyl-tricosa-5,9,13,17,21-pent...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of pig liver squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSqualene monooxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50032855(1-{4-[(3-{[((E)-6,6-Dimethyl-hept-2-en-4-ynyl)-eth...)
Affinity DataIC50:  5.00E+3nMAssay Description:In vitro inhibitory activity against pig liver microsomal squalene epoxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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