Compile Data Set for Download or QSAR
maximum 50k data
Found 6 of ki for monomerid = 50231520
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
University of Antwerp (Ua)

Curated by ChEMBL
LigandPNGBDBM50231520((R)-N-[(S)-1-(4-carbamimidoyl-benzylcarbamoyl)-2-h...)
Affinity DataKi:  20nMAssay Description:Inhibition of human uPAMore data for this Ligand-Target Pair
TargetSerine protease 1(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM50231520((R)-N-[(S)-1-(4-carbamimidoyl-benzylcarbamoyl)-2-h...)
Affinity DataKi:  22nM ΔG°:  -43.6kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against TrypsinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetUrokinase plasminogen activator surface receptor(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM50231520((R)-N-[(S)-1-(4-carbamimidoyl-benzylcarbamoyl)-2-h...)
Affinity DataKi:  25nM ΔG°:  -43.2kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against Plasminogen activator urokinaseMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransmembrane protease serine 11D(Homo sapiens (Human))
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50231520((R)-N-[(S)-1-(4-carbamimidoyl-benzylcarbamoyl)-2-h...)
Affinity DataKi:  78nMAssay Description:Inhibition of human recombinant airway trypsin-like protease HAT using D-cyclohexylalanine-Pro-Arg-AMC as substrate by fluorescence plate reader anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM50231520((R)-N-[(S)-1-(4-carbamimidoyl-benzylcarbamoyl)-2-h...)
Affinity DataKi:  750nM ΔG°:  -34.8kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM50231520((R)-N-[(S)-1-(4-carbamimidoyl-benzylcarbamoyl)-2-h...)
Affinity DataKi:  1.40E+4nM ΔG°:  -27.6kJ/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent