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Found 3 of ki for monomerid = 60886
TargetHypoxanthine-guanine-xanthine phosphoribosyltransferase(Plasmodium falciparum)
The University of Queensland

US Patent
LigandPNGBDBM60886(US9200020, Table 3, Compound 1B)
Affinity DataKi:  1.90E+3nM ΔG°:  -34.0kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine-guanine phosphoribosyltransferase(Homo sapiens (Human))
The University of Queensland

US Patent
LigandPNGBDBM60886(US9200020, Table 3, Compound 1B)
Affinity DataKi:  2.60E+3nM ΔG°:  -33.2kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHypoxanthine phosphoribosyltransferase(Plasmodium vivax)
The University of Queensland

US Patent
LigandPNGBDBM60886(US9200020, Table 3, Compound 1B)
Affinity DataKi:  1.10E+4nM ΔG°:  -29.4kJ/moleT: 2°CAssay Description:The [3H]-hypoxanthine growth inhibition assay (Desjardins et al., 1979 Antimicrobial Agents Chemother 16: 710-718) was used to evaluate the in vitr...More data for this Ligand-Target Pair
In DepthDetails US Patent