Compile Data Set for Download or QSAR
maximum 50k data
Found 29 Enz. Inhib. hit(s) with all data for entry = 50018979
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50614397(CHEMBL5279386)
Affinity DataKi:  6nMAssay Description:Binding affinity to heparanase (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50614394(CHEMBL5273238)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50614394(CHEMBL5273238)
Affinity DataIC50:  0.0800nMAssay Description:Inhibition of human heparanase using fondaparinux as substrate incubated for 18 hrs by Polymer-H fluorescence assayMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50614397(CHEMBL5279386)
Affinity DataIC50:  12nMAssay Description:Inhibition of heparanase (unknown origin) incubated for 18 hrs by fondaparinux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50614398(CHEMBL5268939)
Affinity DataIC50:  20nMAssay Description:Inhibition of heparanase (unknown origin) incubated for 18 hrs by fondaparinux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetP-selectin(Mus musculus)TBA
LigandPNGBDBM50614401(CHEMBL5269532)
Affinity DataIC50:  150nMAssay Description:Inhibition of mouse P-selectin assessed as inhibition of adhesion to human LS180 cells to immobilized P-selectin incubated for 1 hrs by ELISAMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50614402(CHEMBL5285151)
Affinity DataIC50:  200nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50412102(CHEMBL495255)
Affinity DataIC50:  200nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50147546(2-(3-(5-(benzo[d][1,3]dioxol-5-yl)benzo[d]oxazol-2...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50165639((2-{4-[2-(2,4-Dichloro-phenylcarbamoyl)-vinyl]-2-f...)
Affinity DataIC50:  200nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50147534(1,3-Dioxo-2-[3-(5-phenyl-benzooxazol-2-yl)-4-propy...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50147537(2-(5-(5-(4-fluorophenyl)benzo[d]oxazol-2-yl)-2-met...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50165652((2-{4-[3-((E)-4-Bromo-phenyl)-acryloylamino]-3-flu...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50165636(2-(4-(5-(4-(3-(4-bromophenyl)acrylamido)-2-chlorop...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50614399(CHEMBL5266136)
Affinity DataIC50:  416nMAssay Description:Inhibition of heparanase (unknown origin) incubated for 18 hrs by fondaparinux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50165660(2-(3-(5-(4-chlorophenyl)benzo[d]oxazol-2-yl)-4-(pr...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50614395(CHEMBL5279972)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50614400(CHEMBL5286425)
Affinity DataIC50:  4.82E+3nMAssay Description:Inhibition of heparanase (unknown origin) incubated for 18 hrs by fondaparinux assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50147526(2-(3-(benzo[d]oxazol-2-yl)phenyl)-1,3-dioxoisoindo...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50147508(2-(2-methoxy-5-(5-(2-methoxyphenyl)benzo[d]oxazol-...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50614396(CHEMBL5270472)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50147532(2-[4-Methylamino-3-(5-phenyl-benzooxazol-2-yl)-phe...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50431651(CHEMBL2349236)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50093526(CHEMBL426373 | RK-682)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50614393(CHEMBL5279103)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50614392(CHEMBL276295)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50595401(CHEMBL5175115)
Affinity DataIC50:  3.60E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50179360(CHEMBL3040216)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))TBA
LigandPNGBDBM50611971(CHEMBL5280887)
Affinity DataIC50:  6.50E+4nMAssay Description:Inhibition of heparanase (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed