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Found 2 Enz. Inhib. hit(s) with Target = 'ATP-dependent translocase ABCB1' and Ligand = 'BDBM50249852'
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50249852(3,6-Bis(dimethylamino)-9-(N-piperidyl-2-thienyl-5-...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of verapamil-stimulated ATPase activity of human histidine10-tagged MDR1 expressed in BHK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
The State University Of New York

Curated by ChEMBL
LigandPNGBDBM50249852(3,6-Bis(dimethylamino)-9-(N-piperidyl-2-thienyl-5-...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human MDR1 expressed in MDCK2 cells assessed as enhancement of Calcein-AM uptake treated 30 mins before Calcein-AM challenge measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed