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Found 2 Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM153270'
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM153270(3,5,7-trihydroxy-2-(2-hydroxyphenyl)chromen-4-one ...)
Affinity DataIC50:  5.54E+4nMAssay Description:Inhibition of wild type Amyloid beta (1 to 42) (unknown origin) aggregation by Thioflavin-T fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Kyoto University

Curated by ChEMBL
LigandPNGBDBM153270(3,5,7-trihydroxy-2-(2-hydroxyphenyl)chromen-4-one ...)
Affinity DataIC50:  5.54E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence intensity was measured at 420 nm excitation and 485 nm emission using a microplate reader (MPR-A4ιII; TOSOH, Tokyo, Japan, or Fluoroska...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed