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Found 2 Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM50220273'
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50220273(1-((2R,6R)-1-(3,5-difluorophenylsulfonyl)-6-ethylp...)
Affinity DataIC50:  29nMAssay Description:Inhibition of gamma-secretase assessed as reduction of membrane Abeta40 levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50220273(1-((2R,6R)-1-(3,5-difluorophenylsulfonyl)-6-ethylp...)
Affinity DataIC50:  144nMAssay Description:Inhibition of gamma-secretase assessed as reduction of cell Abeta40 levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed