Found 4 Enz. Inhib. hit(s) with Target = 'Broad substrate specificity ATP-binding cassette transporter ABCG2' and Ligand = 'BDBM50379209' TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Cnrs/Universit£
Curated by ChEMBL
Cnrs/Universit£
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of ABCG2-mediated mitoxantrone efflux in HEK293 cells by flow cytometryMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Cnrs/Universit£
Curated by ChEMBL
Cnrs/Universit£
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of human ABCG2 expressed in HEK293 cells by mitoxantrone flow cytometric analysisMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Cnrs/Universit£
Curated by ChEMBL
Cnrs/Universit£
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of ABCG2 in topotecan-cultured human MCF7 cells using Hoechst 33342 as substrate measured after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Cnrs/Universit£
Curated by ChEMBL
Cnrs/Universit£
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells by Hoechst 33342 assayMore data for this Ligand-Target Pair
