Found 6 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 2' and Ligand = 'BDBM50363953'
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human CCR2-mediated Erk phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I]MCP1 from human CCR2 in PBMC after 30 mins by gamma countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Displacement of [125I]MCP1 from CCR2 in human PBMC after 30 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis after 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Antagonist activity at CCR2 receptor in human PBMC assessed as inhibition of MCP1-mediated leukocyte chemotaxis after 30 mins by microscopyMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of human CCR2-mediated intracellular calcium mobilization by cell based assayMore data for this Ligand-Target Pair