Found 3 Enz. Inhib. hit(s) with Target = 'C-C chemokine receptor type 4' and Ligand = 'BDBM50516626'
Affinity DataIC50: 34nMAssay Description:Antagonist activity at human CCR4 expressed in rat chem-5 cells assessed as inhibition of CCL22-induced calcium flux measured at 2.5 secs time interv...More data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Antagonist activity at CCR4 in human CCRF-CEM cells assessed as inhibition of CCL22-mediated chemotaxis in presence of 100% human serum pre-incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 325nMAssay Description:Antagonist activity at CCR4 in anti-CD3/CD28 stimulated mouse Treg cells assessed as inhibition of CCL22-mediated chemotaxis in presence of 100% huma...More data for this Ligand-Target Pair