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Found
1
Enz. Inhib. hit(s) with Target = 'Coagulation factor XI' and Ligand = 'BDBM598476'
Target
Coagulation factor XI
(Homo sapiens (Human))
Kalvista Pharmaceuticals
US Patent
Ligand
BDBM598476
(1-{1H,2H,3H,5H,6H,10bH-pyrrolo[2,1-a]isoquinolin-9...)
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Affinity Data
IC50: >4.00E+4nM
Assay Description:
FXIa inhibitory activity in vitro was determined using standard published methods (see e.g. Johansen et al., Int. J. Tiss. Reac. 1986, 8, 185; Shori ...
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Ligand Info
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