Affinity DataKi: 4.85E+3nMAssay Description:Mechanism based inhibition of human cytochrome P450 2D6 measured by dextromethorphan O-demethylationMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Cytochrome P450 3A4 and 2D6:Recombinant enzymes, 3A4 and 2D6, generated using the ABL yeast expression system were used. For CYP3A4, the enzyme amou...More data for this Ligand-Target Pair