Affinity DataKi: 148nMAssay Description:Displacement of [125I]IABN from chimeric human D2 receptor possessing extracellular loop II of D3 receptor expressed in HEK293 cell membranes by gamm...More data for this Ligand-Target Pair
Affinity DataKi: 511nMAssay Description:The affinities of the target compounds were determined using radioligand binding experiments. All radioligand binding experiments were performed acco...More data for this Ligand-Target Pair
Affinity DataKi: 511nMAssay Description:Displacement of [125I]IABN from human D2LR expressed in HEK293 cell membranes by gamma counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 511nMAssay Description:Stably transfected HEK cells expressing the human D2-long and the D3 dopamine receptor were developed using the pIRESneo2 bicistronic expression vect...More data for this Ligand-Target Pair
Affinity DataKi: 702nMAssay Description:Displacement of [125I]IABN from wild type human D2R expressed in HEK293 cell membranes by gamma counting methodMore data for this Ligand-Target Pair
Affinity DataIC50: 111nMAssay Description:Antagonist activity against human D2LR expressed in CHO cells assessed as inhibition of dopamine-induced [35S]GTPgammaS binding by dopamine potency s...More data for this Ligand-Target Pair
Affinity DataIC50: 261nMAssay Description:Antagonist activity against human D2LR expressed in CHOK1 cells assessed as inhibition of pergolide-induced beta-arrestin translocation by beta-galac...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity against human D2R expressed in CHO cells assessed as inhibition of quinpirole-induced mitogenesis after 24 hrs by [3H]thymidine u...More data for this Ligand-Target Pair