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Found 5 Enz. Inhib. hit(s) with Target = 'D-3-phosphoglycerate dehydrogenase' and Ligand = 'BDBM50512575'
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Meyer Cancer Center

Curated by ChEMBL
LigandPNGBDBM50512575(CHEMBL4554985)
Affinity DataKi:  214nMAssay Description:Mixed type inhibition of PHGDH (unknown origin) using 3-PG as substrate incubated for 20 mins in presence of , PSAT1, PSPH and varying NAD+ by diapho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Meyer Cancer Center

Curated by ChEMBL
LigandPNGBDBM50512575(CHEMBL4554985)
Affinity DataIC50:  238nMAssay Description:Inhibition of PHGDH (unknown origin) using 140 nM of PHGDH and 3-PG as substrate incubated for 20 mins in presence of NAD+, PSAT1, PSPH by diaphorase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Meyer Cancer Center

Curated by ChEMBL
LigandPNGBDBM50512575(CHEMBL4554985)
Affinity DataIC50:  238nMAssay Description:Inhibition of PHGDH (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Meyer Cancer Center

Curated by ChEMBL
LigandPNGBDBM50512575(CHEMBL4554985)
Affinity DataIC50:  260nMAssay Description:Inhibition of PHGDH (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetD-3-phosphoglycerate dehydrogenase(Homo sapiens (Human))
Meyer Cancer Center

Curated by ChEMBL
LigandPNGBDBM50512575(CHEMBL4554985)
Affinity DataIC50:  5.70E+4nMAssay Description:Inhibition of human PHGDH by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB