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Found 6 Enz. Inhib. hit(s) with Target = 'DNA polymerase catalytic subunit' and Ligand = 'BDBM50370476'
TargetDNA polymerase catalytic subunit(Human herpesvirus 1 (strain KOS) (HHV-1) (Human he...)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50370476(Combivir | ZIDOVUDINE TRIPHOSPHATE)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of HSV1 DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50370476(Combivir | ZIDOVUDINE TRIPHOSPHATE)
Affinity DataIC50:  3.30E+3nMpH: 7.5Assay Description:Inhibition of herpes simplex virus type 1 DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50370476(Combivir | ZIDOVUDINE TRIPHOSPHATE)
Affinity DataIC50:  5.80E+3nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Varicella-zoster virus (strain Dumas) (HHV-3) (Hum...)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50370476(Combivir | ZIDOVUDINE TRIPHOSPHATE)
Affinity DataIC50:  5.80E+3nMpH: 7.5Assay Description:Inhibition of Varicella-Zoster virus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50370476(Combivir | ZIDOVUDINE TRIPHOSPHATE)
Affinity DataIC50:  2.21E+4nMAssay Description:Inhibition of HCMV DNA polymerase by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA polymerase catalytic subunit(Human cytomegalovirus (HCMV strain AD169) )
Pfizer

Curated by ChEMBL
LigandPNGBDBM50370476(Combivir | ZIDOVUDINE TRIPHOSPHATE)
Affinity DataIC50:  2.21E+4nMpH: 7.5Assay Description:Inhibition of human cytomegalovirus DNA polymerase (95 uL) activity in a solution containing 6.4 mM HEPES (pH 7.5), incubation for 12 minutes at 26 d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed