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Found
1
Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase XIAP [124-240]' and Ligand = 'BDBM50441829'
Target
E3 ubiquitin-protein ligase XIAP [124-240]
(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Ligand
BDBM50441829
(CHEMBL2436331 | US10053431, 75a)
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Affinity Data
IC50: 8nM
pH: 7.5 T: 2°C
Assay Description:
Ten nanomolar of 6× Histidine-tagged BIR2 domain, corresponding to amino acids 124-240 of XIAP, or BIR3 domain, corresponding to amino acids 241-356 ...
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