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Found 2 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50453577'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50453577(CHEMBL354128)
Affinity DataIC50:  400nMAssay Description:Inhibitory potency against protein tyrosine kinase activity associated with EGFR was evaluated using ER 22 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of Paris

Curated by ChEMBL
LigandPNGBDBM50453577(CHEMBL354128)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of EGF-stimulated DNA synthesis in ER22 cells, by measuring [3H]Me-dT incorporation into ER 22 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed