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Found 4 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM561454'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
H. R. Patel Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM561454(US11390625, Compound 34 | US11390625, Example 34)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
H. R. Patel Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM561454(US11390625, Compound 34 | US11390625, Example 34)
Affinity DataIC50:  0.218nMAssay Description:Inhibition of EGFR Del19/T790M/C797S triple mutant (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
H. R. Patel Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM561454(US11390625, Compound 34 | US11390625, Example 34)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of wild type EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
H. R. Patel Institute Of Pharmaceutical Education And Research

Curated by ChEMBL
LigandPNGBDBM561454(US11390625, Compound 34 | US11390625, Example 34)
Affinity DataIC50:  7.92nMAssay Description:TBDMore data for this Ligand-Target Pair
In DepthDetails US Patent