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Found 6 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM50144851'
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  3nMAssay Description:Binding affinity towards human recombinant Estrogen receptor alpha was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]-17-beta-estradiol from full length human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  3nMAssay Description:Binding affinity towards human recombinant Estrogen receptor alpha was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]-17-beta-estradiol from full length human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  9.60nMAssay Description:Potency in cellular transactivation assay utilizing HEK-293 cells stably co-transfected with human estrogen receptor alpha and the alkaline phosphata...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144851((2R,3S)-3-(4-Hydroxy-phenyl)-2-[4-(2-piperidin-1-y...)
Affinity DataIC50:  188nMAssay Description:In vitro binding affinity for Estrogen receptor alpha in HEK-293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed