Found 14 Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 4' and Ligand = 'BDBM50233461' TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of N-terminal 6x-His tagged FGFR4 catalytic domain (445-753 residues) (unknown origin) using IYGEFKKK substrate and [gamma-32P]-ATP incuba...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human FGFR4 using poly (Glu, Tyr)4:1 as substrate incubated for 20 mins followed by [33P]-ATP addition and measured after 120 mins by r...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal GST-fused human FGFR4 (460 to 802 residues) expressed in baculovirus expression system by enzymatic methodMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal GST-fused human FGFR4 cytoplasmic domain (460 to 802(end) amino acids) using CSKtide substrate incubated for 90 minsMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of FGFR4 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Inhibition of His-tagged cytoplasmic recombinant human FGFR4 (781 to 1338 residues) expressed in baculovirus expression system using Tyr 4 peptide as...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of FGFR4 (unknown origin)More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: <10nMAssay Description:In each well of a 384-well plate, 0.5 ng/ul of wild type FGFR-4 (Carna Biosciences, Inc.) was incubated in a total of 12.5 ul of buffer (100 mM HEPES...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of FGFR4 (388 to 802 residues) (unknown origin) using 5-Fluo-Ahx-KKKKEEIYFFFG-NH2 as substrate after 60 mins by microfluidic mobility shif...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant non-phosphorylated FGFR4 kinase domain (442 to 753) (unknown origin) expressed in Sf9 insect cells using 5-Fluo-Ahx-KKKKEEI...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of N-terminal GST fusion tagged human FGFR4 cytoplasmic domain (460 to 802 end residues) expressed in baculovirus expression system preinc...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of N-terminal GST tagged FGFR4 (unknown origin) expressed in baculovirus infected sf21 insect cells incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FGFR4 cytoplasmic domain (781 to 133 residues) expressed in baculovirus expression system using...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
University Of Southern California
Curated by ChEMBL
University Of Southern California
Curated by ChEMBL
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of N-terminal 6x-His tagged FGFR4 C552A mutant (unknown origin) using IYGEFKKK substrate and [gamma-32P]-ATP incubated for 30 mins by scin...More data for this Ligand-Target Pair
