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Found 1 Enz. Inhib. hit(s) with Target = 'GTPase KRas' and Ligand = 'BDBM50539759'
TargetGTPase KRas(Homo sapiens (Human))
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50539759(CHEMBL4646899)
Affinity DataIC50:  6nMAssay Description:Inhibition of KRAS G12C mutant in human NCI-H358 cells assessed as reduction in ERK phosphorylation incubated for 3 hrs by in-cell western methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed