Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Gamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1' and Ligand = 'BDBM28960'
LigandPNGBDBM28960((2R)-2-{[5-chloro-2-(hydroxymethyl)phenyl](4-chlor...)
Affinity DataEC50:  10nMAssay Description:H4 human neuroglioma cells expressing beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced with the conditioned...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28960((2R)-2-{[5-chloro-2-(hydroxymethyl)phenyl](4-chlor...)
Affinity DataEC50:  85nMAssay Description:A Chinese Hamster Ovary cell line stably expressing human beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed