Found 3 Enz. Inhib. hit(s) with Target = 'JAK3/JAK1' and Ligand = 'BDBM50021656' 
Affinity DataIC50: 67nMAssay Description:Inhibition of JAK1/JAK3 in human PBMC assessed as reduction in IL-21-induced STAT3 phosphorylation preincubated for 5 mins followed by IL-21 stimulat...More data for this Ligand-Target Pair
Affinity DataIC50: 259nMAssay Description:Inhibition of JAK1/JAK3 in human whole blood assessed as inhibition of IL-15-induced STAT-5 phosphorylation preincubated for 45 mins followed by IL-1...More data for this Ligand-Target Pair
Affinity DataIC50: 562nMAssay Description:Inhibition of JAK1/JAK3 signaling pathway in human THP-1 cells assessed as reduction in IL-4 induced STAT6 phosphorylation preincubated for 2 hrs fol...More data for this Ligand-Target Pair
