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Found 3 Enz. Inhib. hit(s) with Target = 'Kinesin-like protein KIF11' and Ligand = 'BDBM50216514'
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50216514(4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-1,2,3,4,...)
Affinity DataIC50:  200nMAssay Description:Inhibition of Eg5 ATPase activity expressed in Escherichia coli after 12 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50216514(4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-1,2,3,4,...)
Affinity DataIC50:  200nMAssay Description:Inhibition of recombinant human His-tagged Eg5 (1 to 368 residues) assessed as reduction in ATPase activity by Bradford reagent based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Homo sapiens (Human))
Cnrs-Université

Curated by ChEMBL
LigandPNGBDBM50216514(4-(3-hydroxyphenyl)-7,7-dimethyl-2-thioxo-1,2,3,4,...)
Affinity DataIC50:  200nMAssay Description:Inhibition of human Eg5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed